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West Ham Park In East London

West Ham Park has been owned and maintained by the City of London since 1874, and at 77 acres, is the largest park in the London Borough of Newham. Our aim has always been to provide a wide range of facilities, together with a pleasant and relaxing environment for all our visitors.

Our seven acre ornamental garden will lead you to a variety of horticultural delights, whilst out in the park, a wide range of recreational activities are available throughout the year including sports, guided walks and entertainment on the bandstand in the summer. We are also proud to be one of the few parks in the country with our own nursery, supplying over 200 species of plant for displays in the park, and a number of other open spaces in London.


Open every day of the year, patrolled by full time Park Keepers and supported by closed circuit television, it's no wonder that our one million visitors a year tell us they feel welcome and safe and that we are ‘the most popular park in East London’.

Pervention From AIDS

1. See the articles related on safe sex to learn how to reduce the chance of acquiring or spreading HIV, and other sexually transmitted diseases.
2. Try not to use injected drugs. If IV drugs are used, do not share needles or syringes. Many communities now have needle exchange programs, where you can get rid of used syringes and get new, sterile ones for free. These programs can also provide referrals to addiction treatment.
3. Avoid contact with another person's blood. Protective clothing, masks, and goggles may be appropriate when caring for people who are injured.
4. Anyone who tests positive for HIV can pass the disease to others and should not donate blood, plasma, body organs, or sperm. An infected person should tell any prospective sexual partner about their HIV-positive status. They should not exchange body fluids during sexual activity, and should use whatever preventive measures will give the partner the most protection.
5. HIV-positive women who wish to become pregnant should seek counseling about the risk to unborn children, and medical advances that may help prevent the fetus from becoming infected. Use of certain medications can dramatically reduce the chances that the baby will become infected during pregnancy.
6. Mothers who are HIV-positive should not breast feed their babies.
7. Safe-sex practices, such as latex condoms, are highly effective in preventing HIV transmission. HOWEVER, there remains a risk of acquiring the infection even with the use of condoms. Abstinence is the only sure way to prevent sexual transmission of HIV.

The riskiest sexual behavior is unprotected receptive anal intercourse -- the least risky sexual behavior is receiving oral sex. Performing oral sex on a man is associated with some risk of HIV transmission, but this is less risky than unprotected vaginal intercourse. Female-to-male transmission of the virus is much less likely than male-to-female transmission. Performing oral sex on a woman who does not have her period carries low risk of transmission.

HIV-positive patients who are taking anti-retroviral medications are less likely to transmit the virus. For example, pregnant women who are on effective treatment at the time of delivery, and who have undetectable viral loads, give HIV to the infant less than 1% of the time, compared with about 20% of the time if medications are not used.

The US blood supply is among the safest in the world. Nearly all people infected with HIV through blood transfusions received those transfusions before 1985, the year HIV testing began for all donated blood. Currently, the risk of infection with HIV through a blood transfusion or blood products is almost zero in the United States, even in geographic areas with a lot of HIV infections.

If you believe you have been exposed to HIV, seek medical attention IMMEDIATELY. There is some evidence that an immediate course of antiviral drugs can reduce the chances that you will be infected. This is called post-exposure prophylaxis (PEP), and has been used to treat health care workers injured by needle sticks, to prevent transmission.

There is less information available about how effective PEP is for people exposed to HIV through sexual activity or IV drug use. However, if you believe you have been exposed, you should discuss the possibility with a knowledgeable specialist (check local AIDS organizations for the latest information) as soon as possible. Anyone who has been raped should be offered PEP and should consider its potential risks and benefits.

Coffee's History

The first reported appearance of coffee is in the year 850 in the region of Kaffa (hence its name) of Ethiopia. Out of curiosity some person tasted the red fruits from an unknown tree. Gradually the people of this region began to eat this semi-toasted (by the sun) grains. Those who ate said they felt happy and awake. It is unknown how this plant arrived in Yemen in the fourteenth century. The old shepherds of Yemen discovered that when their goats chewed on the leaves and fruits from some tree the goats became agitated and couldn't sleep at night. The shepherds told this to some monks that lived nearby, who began to make a beverage with these grains. This drink helped them stay up longer. One day one of these monks started burning some branches of the plant and without him noticing, some of the grains fell on the fire. A delicious aroma arose from the fire. This smell attracted the other monks who withdrew the grains from the fire and grounded them to make a better tasting beverage from this powder.

In time this new beverage arrived at the Golden Horn, one of the richest zones in the Ottoman Empire. In Istanbul two merchants, Djems de Damasco and Hakim de Alepo opened the first two known coffee houses side by side. In the middle of the XVII century merchants from the east introduced the beverage to the city of Dogos in Venice. According to historians the first "bottega da caffe" was open on the "Plaza San Marco" in 1645. From Venice coffee went to London where the first establishment was manage by an Italian. It was inaugurated in 1652 near the Saint Michael Cornhill Church.

Anti-Human Growth Hormone

The major isoform of hGH is a polypeptide of 191 amino acids. Human GH1-43 is an amino terminal segment of hGH1-191 which comprises the first 43 amino acids. This peptide is a potent regulator of glucose homeostasis. To facilitate our understanding of the physiological regulation of hGH1-43 an assay to measure its levels in biological fluids and extracts is needed. This communication describes the development of anti-hGH1-43 monoclonal antibodies and their use in the development of an indirect competitive ELISA for the quantification of hGH1-43. Hybridomas were produced by the fusion of FOX-NY myeloma cells with spleen cells taken from a mouse immunized with hGH1-43. The hybridomas were screened for production of antibodies to hGH1-43 by antibody capture ELISA. Hybridomas which produced antibodies reactive to hGH1-43 were cloned by limiting dilution. Three monoclonal hybridomas, CCL-1, CCL-2, and CCL-3 were subsequently obtained. These hybridomas secreted antibodies that were highly reactive towards hGH1-43 but minimally reactive towards hGH1-191. The isotypes of the mAbs secreted by CCL-1, CCL-2 and CCL-3 were all IgG1 kappa as shown by isotype specific antibody capture analysis. An indirect competitive ELISA with a detection limit that ranged from 1 to 10 ng/ml was developed using mAbs from monoclonal hybridoma CCL-3. Dose-response curves for competing hGH1-191, hPRL, and hPL indicated minimal cross-reactivity of mAbs with these hormones and conversely, a high degree of specificity for hGH1-43. Dose-response curves for dilutions of human serum and pituitary extract were parallel to the standard. The availability of a sensitive assay for the measurement of hGH1-43 will help us answer questions regarding the biosynthesis, regulation of secretion, and role of hGH1-43 in the control of glucose homeostasis.

Case History

A 5-month-old infant presented with a history of fever, vomiting for 1 week, and convulsions for 3 days. On physical examination, the child was febrile (38.5°C), continuous convulsions were present, and the pupils were reactive. There was a progressive deterioration of consciousness, leading to coma. There was no significant finding in the cardiovascular system or respiratory system or by abdominal examination. A computed tomography scan showed mild effacement of the basal cisterns and a thin hypodense collection in bilateral frontal convexity, suggesting a possibility of subdural hygroma or subdural effusion.

Laboratory data included a total leukocyte count of 7,300/mm3, with 71% neutrophils, 26% lymphocytes, and 3% eosinophils. The hemoglobin concentration was 10.2 g/dl. No parasites were seen in the peripheral smear. The blood electrolyte picture showed sodium at 133 mmol/liter, potassium at 4.4 mmol/liter, chloride at 95 mmol/liter, bicarbonate at 18.6 mmol/liter, phosphorus at 4.7 mg/dl, blood urea nitrogen at 14 mg/dl, a serum calcium level of 9.2 mg%, and a random blood sugar level of 120 mg/dl.

The cerebrospinal fluid (CSF) was cloudy and hemorrhagic; and analysis showed the presence of sugar at a concentration of 10 mg/dl, proteins at a concentration of 361 mg/dl, and a cell count of 130 cells/mm3, with 80% neutrophils and 20% lymphocytes. Gram staining showed numerous polymorphonuclear leukocytes but no bacteria. Examination of a wet mount showed actively motile trophozoites suggestive of PAM. A Giemsa-stained smear showed trophozoites.

CSF sediment culture on 1.5% nonnutrient agar preseeded with a lawn culture of Escherichia coli yielded oval, motile, flagellated forms of Naegleria fowleri (length, about 15 μm) after 48 h of incubation, as observed in a wet mount preparation

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